Endocrine Abstracts

Introduction: Hyperthyroidism (HT) has been associated with hepatic dysfunction in the presence or absence of congestive heart failure (CHF). Our objective is to study the correlation between the clinical and biological presentation of hepatic abnormalities and the cardiac status.Patients and methods: This retrospective study included 17 patients hospitalized in the endocrinology department of Hedi Chaker Hospital in Sfax over 20 years (1997–2017). ...

Introduction: The adrenocortical carcinoma (ACC) is a primary malignant tumor developed in depends of the adrenal cortex, defined by a Weiss score ≥3. Despite the therapeutic progress, its prognosis is still severe.Patients and methods: This retrospective descriptive study evaluated 4 patients with adrenal corticosteroid followed in the endocrinology department of Sfax - Tunisia between 2010 and 2018.Results: There were 3 wom...

Diabetes is a chronic disease whose associated comorbidities are largely influenced not only by pathology but also by socio-economic conditions. The aim of this study is to investigate the influence of social conditions on the evolution of diabetes. A retrospective, comparative study of 111 patients with type 2 diabetes Follow-up in the Endocrinology-Diabetology department in hospital Hedi Chaker of Sfax. Patients were divided into two groups with unfavorable (G1) and good (G2...

Introduction: The otorhinolaryngologist can be confronted to multiple surprises after a thyroid surgeryCase description: We report the case of a 48 year-old woman admitted with post operative hypocalcaemia (after thyroidectomy?). The patient has a history of hypothyroidism since 5 years. She then presented a cervical swelling. The ultra-sound confirmed the presence of a suspicious thyroid nodule measuring 4 cm. A thyroidectomy was then conducted. Post op...

Introduction: Thyroid dyshormonogenesis (TD) accounts for 15–20% of congenital hypothyroidism (CH). Levothyroxine is the treatment of choice with the immediate goal to raise the serum T4 as rapidly as possible. Surgical treatment is indicated in case of compressive or suspected goiter.Patients and methods: Seventeen patients with thyroid dyshormonogenesis belonging to 4 Tunisian families were included in a descriptive prospective study. They were fo...

Introduction: Congenital adrenal hyperplasia (CAH) is a genetic disease with autosomal recessive inheritance. The deficit in 21-hydroxylase (21-OH) is by far the most common enzyme deficiency CAH, since it represents 95% of the cases. Fertility in wome is found to be reduced due to hormonal, mechanical and psychological factors.Patients and methods: It is about a descriptive and prospective study conducted in 15 patients collected in the endocrinology de...

Introduction: Pituitary abscesses are rare entities that can occur either as primary infections or secondarily to different causes. Primary pituitary abscess arises within a previously healthy gland, while secondary abscess occurs in pituitary gland that harbors a pre-existing lesion (adenoma, craniopharyngioma, or Rathke’s cleft cyst). Only 23 cases of secondarily infected adenomas were reported in the literature.Case report: A 38-years-old man pre...

Introduction: Dysthyroidism is not uncommon during chromosomal aberrations. The objective of this work is to study the characteristics of this association at the epidemiological and clinical levels.Methods: This is a retrospective study of 27 cases of patients with trisomy 21 chromosomal abnormalities (6 cases), klinefelter syndrome (4 cases) and Turner syndrome (17 cases) genetically confirmed, collected at endocrinology service at Sfax University Hospi...

IntroductionCirculating cell-free deoxyribonucleic acid (cfDNA) is a topical subject that has proven its place in oncology. However, its regular use is always compromised by the relatively high cost of the technique. The objective of our study is to determine the usefulness of cfDNA in the management of obese patients with breast cancer as well as its prognostic impact.MethodsUsing real-time multiplex polymer...

IntroductionAltered levels of circulating cell-free deoxyribonucleic acid (ccf DNA) have been found in several pathologies and might have a diagnostic value. With the steadily growing number of studies in the issues related to obesity research, it is proven, that obesity might be related to wide number of body disorders. In the current opinion, we hypothesized that there is a correlation between obesity and elevated cfDNA levels in the circulation.<p...